Srimad Bhagavatam 3:31:15, 16
यन्-माययोरु-गुण-कर्म-निबन्धनेऽस्मिन् सांसारिके पथि चरंस् तद्-अभिश्रमेण ।
नष्ट-स्मृतिः पुनर् अयं प्रवृणीत लोकं युक्त्या कया महद्-अनुग्रहम् अन्तरेण ॥
ज्ञानं यद् एतद् अदधात् कतमः स देवस् त्रै-कालिकं स्थिर-चरेष्व् अनुवर्तितांशः ।
तं जीव-कर्म-पदवीम् अनुवर्तमानास् ताप-त्रयोपशमनाय वयं भजेम ॥
The embodied soul continues a hard struggle for existence, having forgotten the true nature, under the influence of Lord's Maya, traverses the path of repeated birth and death strewn with numerous shackles of Karma. Therefore with out Lord's mercy and grace by what other means can one expect to realize the true nature.
For it is He, who has full of knowledge, and who dwells as an internal consciousness being in all inanimate and animate objects can bestow the true knowledge to the embodied soul.
Therefore, the embodied soul, as a result of karmas, engaged in different activities should pray by Chanting His Divine Names and surrender unto Him in order to get free from the threefold miseries of this conditional life.
Please check these: Excerpts from a discourse by our Sri Sri Muralidhara Swamiji
The sufferings, as per our scriptures, are three-fold – Due to mind / body, due to other embodied beings, due to natural calamities. Surrender to his feet and pray for peace, he shall deliver you from this pain